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Anti-DKK1 Antibody (7O196) is a Rabbit antibody targeting DKK1. Anti-DKK1 Antibody (7O196) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $268 | 7-10 days |
Description | Anti-DKK1 Antibody (7O196) is a Rabbit antibody targeting DKK1. Anti-DKK1 Antibody (7O196) can be used in ELISA. |
Alias | dickkopf WNT signaling pathway inhibitor 1 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 7O196 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human dickkopf related protein 1 (rh Dkk1; TMPY-00775; Met 2-His 266; NP_036374.1). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Dickkopf (DKK) family proteins, consisting of DKK-1, DKK-2, DKK-3 and DKK-4, function as secreted Wnt antagonists by inhibiting Wnt coreceptors LRP5/6. DKK-1, DKK-2, and DKK-4 also bind cell surface Kremen-1 or Kremen-2 and promote the internalization of LRP5/6. Dickkopf related protein 1 (DKK-1) was initially identified as an inducer of head formation in Xenopus embryos. DKK-1 protein modulates Wnt signaling pathway during embryonic development. Increased levels of DKK-1 are found in the majority of lung cancers, esophageal squamous cell carcinomas, and hormone-resistant breast cancers, while DKK-1 expression is decreased in malignant melanoma and colorectal cancers. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human Dkk1 protein (TMPY-00775) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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