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Anti-CAMK1 Antibody (4H22)
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Catalog No. TMAY-02150
Alias CaMKI-α, CaMKI-Alpha, CaM-KI, CAMK1, CaM Kinase I α, CaM Kinase I Alpha, CaM Kinase I, Calcium/Calmodulin-Dependent Protein Kinase Type 1
Anti-CAMK1 Antibody (4H22) is a Rabbit antibody targeting CAMK1. Anti-CAMK1 Antibody (4H22) can be used in ELISA.
Anti-CAMK1 Antibody (4H22)
Anti-CAMK1 Antibody (4H22)
😃Good
Catalog No. TMAY-02150Alias CaMKI-α, CaMKI-Alpha, CaM-KI, CAMK1, CaM Kinase I α, CaM Kinase I Alpha, CaM Kinase I, Calcium/Calmodulin-Dependent Protein Kinase Type 1
Anti-CAMK1 Antibody (4H22) is a Rabbit antibody targeting CAMK1. Anti-CAMK1 Antibody (4H22) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | CaMKI-α, CaMKI-Alpha, CaM-KI, CAMK1, CaM Kinase I α, CaM Kinase I Alpha, CaM Kinase I, Calcium/Calmodulin-Dependent Protein Kinase Type 1 |
| Ig Type | Rabbit IgG |
| Clone | 4H22 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CAMKI / CAMK1 (rh CAMKI / CAMK1; TMPY-04415; NP_003647.1; Leu2-Leu370). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Calcium/calmodulin-dependent protein kinase or CaM kinases are serine/threonine-specific protein kinases that are primarily regulated by the Calcium/calmodulin complex. These kinases show a memory effect on activation. CaM kinases activity can outlast the intracellular calcium transient that is needed to activate it. Inneurons, this property is important for the induction of synaptic plasticity. Pharmacological inhibition of CaM kinases II blocks the induction of long-term potentiation. Upon activation, CaM kinases II phosphorylates postsynaptic glutamate receptors and changes the electrical properties of the synapse. Calcium/calmodulin-dependent protein kinase type 1D, also known as CaM kinase I delta, CaM kinase ID, CaMKI-like protein kinase, CKLiK and CAMK1D, is a member of theprotein kinase superfamily and CaMK subfamily. It contains oneprotein kinase domain. CAMK1D is broadly expressed. It is highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes. Engineered overexpression of CAMK1D in non-tumorigenic breast epithelial cells led to increased cell proliferation, and molecular and phenotypic alterations indicative of epithelial-mesenchymal transition (EMT), including loss of cell-cell adhesions and increased cell migration and invasion. CAMK1D is a potential therapeutic target with particular relevance to clinically unfavorable basal-like tumors. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CAMKI / CAMK1 protein (TMPY-04415) |
| Antigen Species | Human |
| Biology Area | Calcium-binding Proteins and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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