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Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 10 mg | $44 | In Stock | In Stock | |
| 25 mg | $77 | In Stock | In Stock | |
| 50 mg | $113 | In Stock | In Stock | |
| 100 mg | $179 | In Stock | In Stock |
| Description | Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic. |
| Targets&IC50 | parC-gyrA mutants (S. pneumonia):1 μg/ml (MIC) |
| In vivo | Clinafloxacin is an effective broad-spectrum antibiotic exhibiting potent in vitro activity against Gram-positive, Gram-negative, and anaerobic pathogens, and is particularly efficacious against Streptococcus pneumoniae. It demonstrates high activity in Streptococcus pneumoniae strain 7785 (MIC=0.125μg/ml). |
| Synonyms | PD 127391, CI-960, AM-1091 |
| Molecular Weight | 365.79 |
| Formula | C17H17ClFN3O3 |
| Cas No. | 105956-97-6 |
| Smiles | ClC1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N3CC(N)CC3)C4CC4 |
| Relative Density. | 1.573 g/cm3 |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 1.83 mg/mL (5 mM), Sonication is recommended. H2O: 1 mg/mL (2.73 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
H2O/DMSO
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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