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Genevant CL1

🥰Excellent
Catalog No. T75270Cas No. 1450888-71-7
Alias Genevant CL-1

Genevant CL1 (lipid 10) is an ionisable lipid (pKa=6.3) suitable for preparing lipid nanoparticles (LNP) for delivering nucleic acid payloads and intramuscular vaccines.

Genevant CL1

Genevant CL1

🥰Excellent
Catalog No. T75270Alias Genevant CL-1Cas No. 1450888-71-7
Genevant CL1 (lipid 10) is an ionisable lipid (pKa=6.3) suitable for preparing lipid nanoparticles (LNP) for delivering nucleic acid payloads and intramuscular vaccines.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$635-In Stock
10 mg$1,200-In Stock
25 mg$2,370-In Stock
50 mg$3,790-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
Genevant CL1 (lipid 10) is an ionisable lipid (pKa=6.3) suitable for preparing lipid nanoparticles (LNP) for delivering nucleic acid payloads and intramuscular vaccines.
SynonymsGenevant CL-1
Chemical Properties
Molecular Weight588
FormulaC39H73NO2
Cas No.1450888-71-7
SmilesC(C(CCC/C=C\CCCCC)CCC/C=C\CCCCC)(OC(CCCCN(C)C)=O)CCC/C=C\CCCCC
ColorTransparent
AppearanceLiquid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 80 mg/mL (136.05 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.7007 mL8.5034 mL17.0068 mL85.0340 mL
5 mM0.3401 mL1.7007 mL3.4014 mL17.0068 mL
10 mM0.1701 mL0.8503 mL1.7007 mL8.5034 mL
20 mM0.0850 mL0.4252 mL0.8503 mL4.2517 mL
50 mM0.0340 mL0.1701 mL0.3401 mL1.7007 mL
100 mM0.0170 mL0.0850 mL0.1701 mL0.8503 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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