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SARS-CoV-2-IN-13

Name: SARS-CoV-2-IN-13
Brand: TargetMol
SKU: T60919
Price: 31 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T60919Cas No. 56961-10-5

SARS-CoV-2-IN-13 (compound 5) is an analogue of niclosamide, displaying greater stability in human plasma and liver S9 enzymes assay. It improves bioavailability and half-life when administered orally and is a potent SARS-CoV-2 inhibitor with an IC50 of 0.057 μM [1].

SARS-CoV-2-IN-13

🥰Excellent

Purity: 98.54%

Catalog No. T60919Cas No. 56961-10-5

Pack Size	Price	Availability
1 mg	$31	In Stock
5 mg	$73	In Stock
10 mg	$118	In Stock
25 mg	$238	In Stock
50 mg	$353	In Stock
100 mg	$506	In Stock
200 mg	$686	In Stock
1 mL x 10 mM (in DMSO)	$80	In Stock

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Batch Information

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Purity:98.54%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	327.12
Formula	C₁₃H₈Cl₂N₂O₄
Cas No.	56961-10-5
Smiles	Oc1ccc(Cl)cc1C(=O)Nc1ccc(c(Cl)c1)[N+]([O-])=O

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 112.5 mg/mL (343.91 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.0570 mL	15.2849 mL	30.5698 mL	152.8491 mL
5 mM	0.6114 mL	3.0570 mL	6.1140 mL	30.5698 mL
10 mM	0.3057 mL	1.5285 mL	3.0570 mL	15.2849 mL
20 mM	0.1528 mL	0.7642 mL	1.5285 mL	7.6425 mL
50 mM	0.0611 mL	0.3057 mL	0.6114 mL	3.0570 mL
100 mM	0.0306 mL	0.1528 mL	0.3057 mL	1.5285 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc