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Anti-Kallikrein 4/KLK4 Antibody (6N82)
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Catalog No. TMAY-02116
Alias PSTS, PRSS17, KLK-L1, kallikrein-related peptidase 4, kallikrein, EMSP1, EMSP, ARM1, AI2A1
Anti-Kallikrein 4/KLK4 Antibody (6N82) is a Mouse antibody targeting Kallikrein 4/KLK4. Anti-Kallikrein 4/KLK4 Antibody (6N82) can be used in ELISA.
Anti-Kallikrein 4/KLK4 Antibody (6N82)
Anti-Kallikrein 4/KLK4 Antibody (6N82)
😃Good
Catalog No. TMAY-02116Alias PSTS, PRSS17, KLK-L1, kallikrein-related peptidase 4, kallikrein, EMSP1, EMSP, ARM1, AI2A1
Anti-Kallikrein 4/KLK4 Antibody (6N82) is a Mouse antibody targeting Kallikrein 4/KLK4. Anti-Kallikrein 4/KLK4 Antibody (6N82) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | PSTS, PRSS17, KLK-L1, kallikrein-related peptidase 4, kallikrein, EMSP1, EMSP, ARM1, AI2A1 |
| Ig Type | Mouse IgG2b |
| Clone | 6N82 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human KLK4/Kallikrein 4 (rh KLK4/Kallikrein 4; TMPY-01900; NP_004908.3; Met1-Ser254). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Kallikrein-4, also known as Enamel matrix serine proteinase 1, Kallikrein-like protein 1, KLK-L1, Serine protease 17, KLK4, PRSS17, and EMSP1, is a secreted protein that belongs to the peptidase S1 family and Kallikrein subfamily. Kallikrein-4 / KLK4 is a serine protease expressed during enamel maturation, and proteolytic processing of the enamel matrix by KLK4 is critical for proper enamel formation. Kallikrein-4 / KLK4 contains one peptidase S1 domain. Kallikrein-4 / KLK4 is secreted by transition- and maturation-stage ameloblasts. KLK4 aggressively degrades the retained organic matrix following the termination of enamel protein secretion. Two proteases are secreted into the enamel matrix of developing teeth. The early protease is enamelysin (MMP-2). The late protease is kallikrein 4 (KLK4). The principal functions of MMP-2 and KLK4 in dental enamel formation are to facilitate the orderly replacement of organic matrix with mineral, generating an enamel layer that is harder, less porous, and unstained by retained enamel proteins. Defects in Kallikrein-4 / KLK4 are the cause of Amelogenesis Imperfecta Hypomaturation type 2A1 (AI2A1) which is an autosomal recessive defect of enamel formation. The disorder involves both primary and secondary dentitions. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human KLK4/Kallikrein 4 Protein (TMPY-01900) |
| Antigen Species | Human |
| Biology Area | Serine Proteases and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
Sci Citations
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