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Anti-Ribonuclease A Antibody (1N257) is a Rabbit antibody targeting Ribonuclease A. Anti-Ribonuclease A Antibody (1N257) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-Ribonuclease A Antibody (1N257) is a Rabbit antibody targeting Ribonuclease A. Anti-Ribonuclease A Antibody (1N257) can be used in ELISA. |
Alias | RNS1, ribonuclease, RNase A family, 1 (pancreatic), RIB1, RAC1 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1N257 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human RNase A / Ribonuclease A / RNASE1 (rh RNase A / Ribonuclease A / RNASE1; TMPY-03180; P07998; Met1-Thr156). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | RNase A, also known as ribonuclease A and RNASE1, belongs to ribonuclease A superfamily. It is a pancreatic-type of secretory ribonuclease. RNase A is a basic protein and its many positive charges are consistent with its binding to RNA (a poly-anion). More generally, RNase A is unusually polar or, rather, unusually lacking in hydrophobic groups, especially aliphatic ones. As an endonuclease, RNase A cleaves internal phosphodiester RNA bonds on the 3'-side of pyrimidine bases. It prefers poly(C) as a substrate and hydrolyzes 2',3'-cyclic nucleotides, with a pH optimum near 8.0. RNase A is monomeric and more commonly acts to degrade ds-RNA over ss-RNA. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human RNase A / Ribonuclease A / RNASE1 Protein (TMPY-03180) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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