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Anti-ICOS ligand Antibody-FITC (9J164)
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Catalog No. TMAY-01904F
Alias LICOS, inducible T-cell co-stimulator ligand, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP-1, B7RP1, B7-h2, B7H2
Anti-ICOS ligand Antibody-FITC (9J164) is a FITC-conjugated Rabbit antibody targeting ICOS ligand. Anti-ICOS ligand Antibody-FITC (9J164) can be used in FCM.
Anti-ICOS ligand Antibody-FITC (9J164)
Anti-ICOS ligand Antibody-FITC (9J164)
😃Good
Catalog No. TMAY-01904FAlias LICOS, inducible T-cell co-stimulator ligand, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP-1, B7RP1, B7-h2, B7H2
Anti-ICOS ligand Antibody-FITC (9J164) is a FITC-conjugated Rabbit antibody targeting ICOS ligand. Anti-ICOS ligand Antibody-FITC (9J164) can be used in FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 T | $81 | 7-10 days | |
| 100 T | $104 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: FCM Reactivity: Human |
| Alias | LICOS, inducible T-cell co-stimulator ligand, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP-1, B7RP1, B7-h2, B7H2 |
| Ig Type | Rabbit IgG |
| Clone | 9J164 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human ICOSLG (CD275) expression in RPMI8226 cells. |
| Application | FCM |
| Recommended Dose | 10 μl/Test, 0.1 mg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human ICOS Ligand / B7-H2 / ICOSLG (rh ICOS Ligand / B7-H2 / ICOSLG; TMPY-01672; NP_056074.1; Met1-Ser258) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| Research Background | Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains and binds to ICOS on activated T cells, thus delivers a positive costimulatory signal for optimal T cell function. The structural features of ICOSL are crucial for its costimulatory function. The present study shows that ICOSL displays a marked oligomerization potential, resembling more like B7-1 than B7-2. B7-H2-dependent signaling may play an active role in a proliferative response rather than in cytokine and chemokine production. The CD28/B7 and ICOS/B7-H2 pathways are both critical for costimulating T cell immune responses. Deficiency in either pathway results in defective T cell activation, cytokine production, and germinal center formation.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | FITC |
| Immunogen | Recombinant Protein: Human ICOS Ligand / B7-H2 / ICOSLG protein (TMPY-01672) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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