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Vixtimotamab (Synonyms: TandAb T564, AMV-564)
Catalog No. T80858 Copy Product Info
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Vixtimotamab (AMV-564; TandAb T564), a bispecific tetravalent tandem diabody (TandAb), selectively targets human CD33 and CD3 antigens, and is used in acute myeloid leukemia (AML) research [1].
Vixtimotamab
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Catalog No. T80858
Synonyms TandAb T564, AMV-564
Vixtimotamab (AMV-564; TandAb T564), a bispecific tetravalent tandem diabody (TandAb), selectively targets human CD33 and CD3 antigens, and is used in acute myeloid leukemia (AML) research [1].
Vixtimotamab
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $747 | 2-4 weeks | 2-4 weeks | |
| 5 mg | $1,930 | 2-4 weeks | 2-4 weeks | |
| 10 mg | $2,970 | 2-4 weeks | 2-4 weeks |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Storage & Solubility Information
| Description | Vixtimotamab (AMV-564; TandAb T564), a bispecific tetravalent tandem diabody (TandAb), selectively targets human CD33 and CD3 antigens, and is used in acute myeloid leukemia (AML) research [1]. |
| In vitro | Vixtimotamab (TandAb T564; 24 h) induces CD25 and CD69 with EC50 values of 1 pM and 2 pM, respectively [1]. Additionally, Vixtimotamab (TandAb T564; 4 days) promotes T-cell proliferation in PBMCs with an EC50 of 3 pM [1]. Furthermore, Vixtimotamab (TandAb T564; 25 pM, 48 h) exhibits cytotoxicity against HL-60 and KG-1a cells [1]. |
| In vivo | Vixtimotamab (TandAb T564; 0.1-10 μg/mouse, i.v.; 5 days) demonstrated a dose-dependent delay in tumor growth in a prophylactic HL-60 xenografted NOD/scid mouse model [1]. Additionally, vixtimotamab (TandAb T564; 50 μg/mouse/d, i.v.; 7 days) significantly inhibited tumor growth in an established HL-60 xenografted NOD/scid mouse model [1]. |
| Synonyms | TandAb T564, AMV-564 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Target | CD33/CD3 |
| Storage | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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