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Neonuezhenide

Name: Neonuezhenide
Brand: TargetMol
SKU: TN1125
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN1125Cas No. 96382-91-1

Neonuezhenide is a phenolic compound isolated from Ligustrum officinale, which has strong antioxidant effects on free radical-induced hemolysis of red blood cells.

Neonuezhenide

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Purity: 97.56%

Catalog No. TN1125Cas No. 96382-91-1

Neonuezhenide is a phenolic compound isolated from Ligustrum officinale, which has strong antioxidant effects on free radical-induced hemolysis of red blood cells.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$39	-	In Stock
5 mg	$73	-	In Stock
10 mg	$122	-	In Stock
1 mL x 10 mM (in DMSO)	$92	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:97.56%

Appearance:Solid

Color:White

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Neonuezhenide is a phenolic compound isolated from Ligustrum officinale, which has strong antioxidant effects on free radical-induced hemolysis of red blood cells.

In vitro

The ethanol extract of the fruits of Ligustrum lucidum was shown to have inhibitory effects on the hemolysis of red blood cells induced by 2,2'-azo-bis-(2-amidinopropane) dihydrochloride. The bioassay-guided analysis led to the isolation of ten secoiridoid glucosides. Two of them were new, lucidumosides C and D. Their structures were elucidated by spectroscopic methods. The other eight compounds were identified as oleoside dimethyl ester, ligustroside, oleuropein, nuezhenide, isonuezhenide, Neonuezhenide, lucidumoside A, and lucidumoside B.[1]

Chemical Properties

Molecular Weight	702.65
Formula	C₃₁H₄₂O₁₈
Cas No.	96382-91-1
Smiles	C(\C)=C/1\[C@H](CC(OC[C@H]2O[C@@H](OCCC3=CC(O)=C(O)C=C3)[C@H](O)[C@@H](O)[C@@H]2O)=O)C(C(OC)=O)=CO[C@H]1O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
Relative Density.	1.58±0.1 g/cm3 (20 °C, 760 mmHg)

Storage & Solubility Information

Storage

keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (71.16 mM), Sonication is recommended.

H2O: 50 mg/mL (71.16 mM), Sonication is recommended.

Solution Preparation Table

DMSO/H2O

	1mg	5mg	10mg	50mg
1 mM	1.4232 mL	7.1159 mL	14.2318 mL	71.1592 mL
5 mM	0.2846 mL	1.4232 mL	2.8464 mL	14.2318 mL
10 mM	0.1423 mL	0.7116 mL	1.4232 mL	7.1159 mL
20 mM	0.0712 mL	0.3558 mL	0.7116 mL	3.5580 mL
50 mM	0.0285 mL	0.1423 mL	0.2846 mL	1.4232 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc