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Anti-Neuregulin-1/NRG1 Antibody (9S269) is a Rabbit antibody targeting Neuregulin-1/NRG1. Anti-Neuregulin-1/NRG1 Antibody (9S269) can be used in ELISA.
Description | Anti-Neuregulin-1/NRG1 Antibody (9S269) is a Rabbit antibody targeting Neuregulin-1/NRG1. Anti-Neuregulin-1/NRG1 Antibody (9S269) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 9S269 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human NRG1 (rh NRG1; TMPY-02721; Q02297-1; Ser20-Lys241). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a 44-kD glycoprotein that interacts with the NEU / ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. NRG1 is a trophic factor that has been implicated in neural development, neurotransmission, and synaptic plasticity. NRG1 has multiple isoforms that are generated by the usage of different promoters and alternative splicing of a single gene. Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. NRG1 is a schizophrenia candidate gene and plays an important role in brain development and neural function. Schizophrenia is a complex disorder, with etiology likely due to epistasis. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human NRG1 Protein (TMPY-02721) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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