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Anti-GDF-15 Antibody (4S576) is a Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody (4S576) can be used in ELISA, IHC.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μg | $207 | 7-10 days | |
100 μg | $348 | 7-10 days |
Description | Antibody Type: Mouse Monoclonal Application: ELISA, IHC Reactivity: Human |
Alias | RG-1, PTGF-β, PTGFBPTGF-β, PTGFBPTGF-beta, PTGF-beta, PTGFB, Placental TGF-β, Placental TGF-beta, PLAB, PDF, NAG-1, MIC-1, MIC1, GDF-15, GDF15 |
Ig Type | IgG2a |
Clone | 4S576 |
Reactivity | Human |
Verified Activity | Immunohistochemistry of paraffin-embedded human adrenal gland using TMAH-00480 in 30μg/ml dilute concentrations. |
Application | ELISA, IHC |
Antibody Type | Monoclonal |
Host Species | Mouse |
Subcellular Localization | Secreted. |
Construction | Hybridoma Monoclonal Antibody |
Purification | Protein G purified |
Appearance | Liquid |
Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
Purity | >95% |
Research Background | Regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. Binds to its receptor, GFRAL, and activates GFRAL-expressing neurons localized in the area postrema and nucleus tractus solitarius of the brainstem. It then triggers the activation of neurons localized within the parabrachial nucleus and central amygdala, which constitutes part of the 'emergency circuit' that shapes feeding responses to stressful conditions. On hepatocytes, inhibits growth hormone signaling. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: GDF15 Protein |
Antigen Species | Human |
Gene ID | 9518 |
Uniprot ID | |
Biology Area | Cell Biology |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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