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Chlorobenzothiazolinone

Name: Chlorobenzothiazolinone
Brand: TargetMol
SKU: T0577
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0577Cas No. 20600-44-6

Chlorobenzothiazolinone inhibits recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay with activity value of 90 μM.

Chlorobenzothiazolinone

🥰Excellent

Purity: 99.77%

Catalog No. T0577Cas No. 20600-44-6

Chlorobenzothiazolinone inhibits recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay with activity value of 90 μM.

Pack Size	Price	Availability
500 mg	$39	In Stock
1 g	$55	In Stock
2 g	$81	In Stock
5 g	$137	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock

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Batch Information

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Purity:99.77%

Resource Download

COA HPLC LCMS

Product Introduction

Bioactivity

Description

Chlorobenzothiazolinone inhibits recombinant human chymase using bis(succinoyl-L-alanyl-L-prolyl-L-phenylalanylamide) as substrate after 1 hr by fluorescence assay with activity value of 90 μM.

Chemical Properties

Molecular Weight	185.63
Formula	C₇H₄ClNOS
Cas No.	20600-44-6
Smiles	ClC1=CC=C2SC(=O)NC2=C1
Relative Density.	1.515g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 11 mg/mL (59.26 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.3871 mL	26.9353 mL	53.8706 mL	269.3530 mL
5 mM	1.0774 mL	5.3871 mL	10.7741 mL	53.8706 mL
10 mM	0.5387 mL	2.6935 mL	5.3871 mL	26.9353 mL
20 mM	0.2694 mL	1.3468 mL	2.6935 mL	13.4677 mL
50 mM	0.1077 mL	0.5387 mL	1.0774 mL	5.3871 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc