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C3a (70-77) (TFA)

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Catalog No. T75966
Alias Complement 3a (70-77) TFA, C3a (70-77) TFA

C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.

C3a (70-77) (TFA)

C3a (70-77) (TFA)

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Purity: 99.92%
Catalog No. T75966Alias Complement 3a (70-77) TFA, C3a (70-77) TFA
C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$64-In Stock
5 mg$156-In Stock
10 mg$263-In Stock
25 mg$446-In Stock
50 mg$645-In Stock
100 mg$886-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:99.92%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
C3a (70-77) (TFA) (Complement 3a (70-77) TFA) is an octapeptide derived from the COOH-terminus of Complement 3a, exhibiting 1–2% C3a biological activity.
In vitro
The generation of LIF activity was inhibited by 50% by 10(-8) M C3a or C3a (70-77) (TFA) with PHA or Con A as the stimulus, whereas a more than 10-fold higher concentration of C3a (70-77) (TFA) than C3a was required to achieve the same level of suppression with SK-SD as the stimulus [1].
SynonymsComplement 3a (70-77) TFA, C3a (70-77) TFA
Chemical Properties
Molecular Weight937.96
FormulaC37H62F3N13O12
SmilesC[C@H](N)C(N[C@@H](CO)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
SequenceAla-Ser-His-Leu-Gly-Leu-Ala-Arg
Sequence ShortASHLGLAR
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 80 mg/mL (85.29 mM), Sonication is recommended.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM1.0661 mL5.3307 mL10.6614 mL53.3072 mL
5 mM0.2132 mL1.0661 mL2.1323 mL10.6614 mL
10 mM0.1066 mL0.5331 mL1.0661 mL5.3307 mL
20 mM0.0533 mL0.2665 mL0.5331 mL2.6654 mL
50 mM0.0213 mL0.1066 mL0.2132 mL1.0661 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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