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Anti-NAALADL1 Antibody (7I736) is a Rabbit antibody targeting NAALADL1. Anti-NAALADL1 Antibody (7I736) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $269 | 7-10 days |
Description | Anti-NAALADL1 Antibody (7I736) is a Rabbit antibody targeting NAALADL1. Anti-NAALADL1 Antibody (7I736) can be used in ELISA. |
Alias | N-acetylated α-linked acidic dipeptidase-like 1, N-acetylated alpha-linked acidic dipeptidase-like 1, Naaladasel, Gm964 |
Ig Type | Monoclonal Rabbit IgG |
Clone | 7I736 |
Reactivity | Mouse |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse NAALADL1 (TMPY-02668; Q7M758; Pro29-Leu745). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | N-acetylated-alpha-linked acidic dipeptidase-like protein, also known as NAALADL1, NAALADase L, and Ileal dipeptidyl-peptidase, is a Single-pass type II membrane protein and a member of the peptidase M28 family and M28B subfamily. NAALADase L is mainly expressed in the distal small intestine. It is also expressed in the spleen and testis and Weakly expressed in the brain, locating mainly to the brain stem, amygdala, thalamus, and ventral striatum. NAALADase L is a chloride-activated, membrane-bound, metallopeptidase that cleaves the endogenous neuropeptide N-acetyl-aspartyl-glutamate (NAAG). NAAG acts as a partial NMDA agonist as well as a full agonist at the presynaptic metabotropic glutamate receptor 3 (mGluR3), where it acts to reduce glutamate release. NAALADase L also exhibits a dipeptidyl-peptidase IV type activity. NAALADase inhibition may be a novel therapeutic approach to reduce or inhibit heightened aggressiveness, and possibly to treat aggressive behavior associated with psychiatric disorders. |
Conjucates | Unconjugated |
Immunogen | Recombinant Mouse NAALADL1 protein (TMPY-02668) |
Antigen Species | Mouse |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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