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Mocravimod hydrochloride

Name: Mocravimod hydrochloride
Brand: TargetMol
SKU: T12086
Price: 64 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T12086Cas No. 509088-69-1

Alias KRP-203

Mocravimod hydrochloride (KRP-203) is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1).

Mocravimod hydrochloride

🥰Excellent

Catalog No. T12086Alias KRP-203Cas No. 509088-69-1

Mocravimod hydrochloride (KRP-203) is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1).

Pack Size	Price	Availability
1 mg	$64	In Stock
5 mg	$172	In Stock
10 mg	$278	In Stock
25 mg	$563	In Stock
50 mg	$872	In Stock
100 mg	$1,170	In Stock
1 mL x 10 mM (in DMSO)	$182	In Stock

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Product Introduction

Bioactivity

Description	Mocravimod hydrochloride (KRP-203) is an effecitive and orally active agonist of sphingosine 1-phosphate receptor type 1(S1PR1).
In vivo	In mHC-disparate rat heart allografts, Mocravimod hydrochloride(orally; 0.1 and 1 mg/kg/day; for 100 days) prolongs graft survival and attenuates chronic rejection[1]. Mocravimod hydrochloride ameliorates atherosclerosis in LDL-R(-/-) Mice[2].
Synonyms	KRP-203

Chemical Properties

Molecular Weight	480.45
Formula	C₂₄H₂₇Cl₂NO₃S
Cas No.	509088-69-1
Smiles	Cl.NC(CO)(CO)CCc1ccc(Sc2cccc(OCc3ccccc3)c2)cc1Cl
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 95 mg/mL (197.73 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.0814 mL	10.4069 mL	20.8138 mL	104.0691 mL
5 mM	0.4163 mL	2.0814 mL	4.1628 mL	20.8138 mL
10 mM	0.2081 mL	1.0407 mL	2.0814 mL	10.4069 mL
20 mM	0.1041 mL	0.5203 mL	1.0407 mL	5.2035 mL
50 mM	0.0416 mL	0.2081 mL	0.4163 mL	2.0814 mL
100 mM	0.0208 mL	0.1041 mL	0.2081 mL	1.0407 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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