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Ongericimab
(Synonyms: JS002) Copy Product Info
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Synonyms: JS002
Catalog No. T77113 Copy Product Info
🥰Excellent
Ongericimab (JS002) is a recombinant humanized monoclonal antibody targeting proprotein convertase subtilisin/kexin type 9 (PCSK9). By blocking the binding of PCSK9 to the low-density lipoprotein receptor (LDLR), the antibody reduces LDLR degradation, thereby increasing hepatic LDL-C uptake and lowering plasma cholesterol levels. It is primarily used to research hypercholesterolemia and cardiovascular risk management.
Ongericimab
Cas No. 2145096-91-7
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
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Related Conjugates and Formulations
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Chemical Properties
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| Description | Ongericimab (JS002) is a recombinant humanized monoclonal antibody targeting proprotein convertase subtilisin/kexin type 9 (PCSK9). By blocking the binding of PCSK9 to the low-density lipoprotein receptor (LDLR), the antibody reduces LDLR degradation, thereby increasing hepatic LDL-C uptake and lowering plasma cholesterol levels. It is primarily used to research hypercholesterolemia and cardiovascular risk management. |
| Synonyms | JS002 |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | PCSK9 |
| Cas No. | 2145096-91-7 |
| Isotype | IgG4 (S228P) |
| Recommended Isotype Control |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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