Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2B receptors, with respective potency values of EC 50 = 32 μM and IC 50 = 27 μM. Its primary mechanism of action involves the modulation of serotonergic and noradrenergic pathways. Viloxazine is commonly employed in depression research [1] [2].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 440.00 | |
10 mg | In stock | $ 648.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,390.00 | |
100 mg | In stock | $ 1,870.00 | |
500 mg | In stock | $ 3,730.00 |
Description | Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2B receptors, with respective potency values of EC 50 = 32 μM and IC 50 = 27 μM. Its primary mechanism of action involves the modulation of serotonergic and noradrenergic pathways. Viloxazine is commonly employed in depression research [1] [2]. |
Targets&IC50 | 5-HT2B:27 μM, 5-HT2C:32 μM(EC50) |
In vivo | Viloxazine (1-16 mg/kg; spinal rat) stimulated the hind limb flexor reflex in the dose-dependent manner.[3] |
Synonyms | Emovit, Viloxazin |
Molecular Weight | 237.29 |
Formula | C13H19NO3 |
CAS No. | 46817-91-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (252.86 mM)
You can also refer to dose conversion for different animals. More
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Viloxazine 46817-91-8 GPCR/G Protein Neuroscience 5-HT Receptor Norepinephrine Emovit Viloxazin inhibitor inhibit