Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, and can be used to improve early embryonic development.BML-278 induces cell cycle arrest in primary human mesenchymal stromal cells at the G1/S phase, and can be used to delay senescence.BML-278 reduces microtubule protein acetylation in U937 cells and increases mitochondrial density in mouse C2C12 myoblasts. BML-278 reduces microtubule protein acetylation in U937 cells and increases mitochondrial density in mouse C2C12 myoblasts.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | In stock | $ 58.00 | |
10 mg | In stock | $ 91.00 | |
25 mg | In stock | $ 166.00 | |
50 mg | In stock | $ 249.00 | |
100 mg | In stock | $ 336.00 | |
500 mg | In stock | $ 740.00 |
Description | BML-278 is a SIRT1 activator with an EC150 of 1 μM.BML-278 increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, and can be used to improve early embryonic development.BML-278 induces cell cycle arrest in primary human mesenchymal stromal cells at the G1/S phase, and can be used to delay senescence.BML-278 reduces microtubule protein acetylation in U937 cells and increases mitochondrial density in mouse C2C12 myoblasts. BML-278 reduces microtubule protein acetylation in U937 cells and increases mitochondrial density in mouse C2C12 myoblasts. |
Targets&IC50 | SIRT1:1 μM(EC50) |
Synonyms | BML278, BML 278 |
Molecular Weight | 391.46 |
Formula | C24H25NO4 |
CAS No. | 120533-76-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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BML-278 120533-76-8 Chromatin/Epigenetic DNA Damage/DNA Repair Histone Methyltransferase Sirtuin BML278 BML 278 inhibitor inhibit