Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

ACTH (1-17) acetate

Copy Product Info
😃Good
TargetMol
Catalog No. TP1011L

ACTH (1-17) acetate is a potent agonist at the human melanocortin 1 (MC1) receptor with high affinity(Ki = 0.21 nM).

ACTH (1-17) acetate
Other Forms of ACTH (1-17) acetate:

ACTH (1-17) acetate

Copy Product Info
😃Good
TargetMol
Purity: 98.53%
Catalog No. TP1011L
ACTH (1-17) acetate is a potent agonist at the human melanocortin 1 (MC1) receptor with high affinity(Ki = 0.21 nM).
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$122In StockIn Stock
5 mg$411In StockIn Stock
10 mg$587In StockIn Stock
25 mg$1,057In StockIn Stock
50 mg$1,585In StockIn Stock
100 mg$2,377-In Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:98.53%
Appearance:Solid
Color:White
Contact us for more batch information

Resource Download

COA HPLC MS

Product Introduction

Bioactivity
Description
ACTH (1-17) acetate is a potent agonist at the human melanocortin 1 (MC1) receptor with high affinity(Ki = 0.21 nM).
Targets&IC50
MC1R (human):0.21 nM(Ki)
In vitro
ACTH (1-17) acetate induces a slight and not significant increase in growth hormone secretion even when micromolar concentrations of the peptide are employed in rat pituitary cultures[1]. ACTH (1-17) acetate showed an affinity for alpha-MSH with Ki of 0.13±0.005 nM[1].
In vivo
When nocturnal animals became active, inhibition of DNA markers was noted when ACTH (1-17) acetate was administered 2 hours after the start of the daily dark span. When administered during this circadian phase, particularly larger doses were associated with a 24-hour lasting inhibition of DNA markers. When the same dose was injected 4 hours earlier, the inhibitory effect was much shorter [2].
Chemical Properties
Molecular Weight2153.47
FormulaC97H149N29O25S
SmilesCC(O)=O.N=C(N)NCCC[C@@H](C(O)=O)NC([C@H](CCCCN)NC([C@H](CCCCN)NC(CNC([C@H](C(C)C)NC([C@H]1N(C([C@H](CCCCN)NC(CNC([C@H](CC2=CNC3=C2C=CC=C3)NC([C@H](CCCNC(N)=N)NC([C@H](CC4=CC=CC=C4)NC([C@H](CC5=CNC=N5)NC([C@H](CCC(O)=O)NC([C@H](CCSC)NC([C@H](CO)NC([C@H](CC6=CC=C(O)C=C6)NC([C@H](CO)N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1)=O)=O)=O)=O)=O
SequenceSer-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg
Sequence ShortSYSMEHFRWGKPVGKKR
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

MelanocortinReceptorMelanocortin ReceptorhMC1RACTH (117) acetateACTH (1 17) acetateACTH AcetateACTH
Related Tags: buy ACTH (1-17) acetate | purchase ACTH (1-17) acetate | ACTH (1-17) acetate cost | order ACTH (1-17) acetate | ACTH (1-17) acetate chemical structure | ACTH (1-17) acetate in vivo | ACTH (1-17) acetate in vitro | ACTH (1-17) acetate formula | ACTH (1-17) acetate molecular weight
TargetMol | Logo

Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.