Powder: -20°C for 3 years | In solvent: -80°C for 1 year
M826, a non-peptide, potent, selective, and reversible caspase-3 inhibitor, exhibits an IC50 of 0.005 μM and demonstrates strong anti-apoptotic activity in vitro and in vivo animal models. It is useful for research into nervous system diseases [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | Inquiry | |
50 mg | Inquiry | Inquiry |
Description | M826, a non-peptide, potent, selective, and reversible caspase-3 inhibitor, exhibits an IC50 of 0.005 μM and demonstrates strong anti-apoptotic activity in vitro and in vivo animal models. It is useful for research into nervous system diseases [1]. |
In vitro | M826 inhibits apoptosis in NT2 cells at varying concentrations after 20-hour exposure [1]. |
In vivo | M826 (30 nmol, intraventricular injection) inhibits the activation of Caspase-3 and the cleavage of its substrates in a neonatal hypoxia-ischemia (H-I) rat model [1]. |
Molecular Weight | 575.7 |
Formula | C28H45N7O6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
M826 Apoptosis Proteases/Proteasome Caspase inhibitor inhibit