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Anti-FGFR2 Antibody (4V380) is an antibody targeting FGFR2. Anti-FGFR2 Antibody (4V380) can be used in ELISA, WB.
Description | Anti-FGFR2 Antibody (4V380) is an antibody targeting FGFR2. Anti-FGFR2 Antibody (4V380) can be used in ELISA, WB. |
Alias | TK25, TK14, K-SAM, KGFR, JWS, FLJ98662, FGFR2 α (IIIb), FGFR2 α, FGFR2 alpha, FGF R2a, ECT1, CFD1, CEK3, CD332, BFR-1, BEK, BBDS |
Ig Type | Rabbit IgG |
Clone | 4V380 |
Reactivity | Human, Mouse, Rat |
Verified Activity | Western Blot -Positive WB detected in: Rat Brain whole cell lysate, Rat Lung whole cell lysate, Mouse Brain whole cell lysate -All lanes: FGFR2 Antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 93, 87, 93, 77, 92, 89, 86, 29, 80, 93, 97, 92, 41, 80, 80, 77, 80 kDa -Observed band size: 145 kDa |
Application | ELISA, WB |
Recommended Dose | WB:1:500-1:5000. |
Antibody Type | Monoclonal |
Subcellular Localization | Cell membrane; Single-pass type I membrane protein. Golgi apparatus. Cytoplasmic vesicle. Note=Detected on osteoblast plasma membrane lipid rafts. After ligand binding, the activated receptor is rapidly internalized and degraded.; [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Note=After ligand binding, the activated receptor is rapidly internalized and degraded.; [Isoform 3]: Cell membrane; Single-pass type I membrane protein. Note=After ligand binding, the activated receptor is rapidly internalized and degraded.; [Isoform 8]: Secreted.; [Isoform 13]: Secreted. |
Construction | Recombinant Antibody |
Purification | Affinity-chromatography |
Appearance | Liquid |
Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Research Background | Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation, migration and apoptosis, and in the regulation of embryonic development. Required for normal embryonic patterning, trophoblast function, limb bud development, lung morphogenesis, osteogenesis and skin development. Plays an essential role in the regulation of osteoblast differentiation, proliferation and apoptosis, and is required for normal skeleton development. Promotes cell proliferation in keratinocytes an... |
Conjucates | Unconjugated |
Immunogen | A synthesized peptide derived from human FGFR2 |
Antigen Species | Human |
Gene ID | 2263 |
Uniprot ID | |
Biology Area | Neuroscience, Cancer, Cardiovascular, Developmental biology, Signal transduction, Stem cells |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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