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Atractylenolide I

Name: Atractylenolide I
Brand: TargetMol
SKU: T5S0167
Price: 36 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T5S0167Cas No. 73069-13-3

1. Atractylenolide-I has an anti-inflammatory effect by inhibiting TNF-α and IL-6 production; ameliorates sepsis syndrome, liver and kidney functions by reduction of pro-inflammatory cytokines and LPS. 2. Atractylenolide-I significantly sensitizes the response of MyD88(+) EOC cells to paclitaxel by blocking MD-2-mediated TLR4/MyD88 signaling.

Atractylenolide I

🥰Excellent

Purity: 99.92%

Catalog No. T5S0167Cas No. 73069-13-3

Pack Size	Price	Availability
1 mg	$36	In Stock
5 mg	$79	In Stock
10 mg	$133	In Stock
25 mg	$253	In Stock
50 mg	$446	In Stock
100 mg	$623	In Stock
1 mL x 10 mM (in DMSO)	$96	In Stock

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Batch Information

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Purity:99.92%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	230.3
Formula	C₁₅H₁₈O₂
Cas No.	73069-13-3
Smiles	CC1=C2C[C@H]3C(=C)CCC[C@]3(C)C=C2OC1=O
Relative Density.	1.12
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

keep away from direct sunlight,keep away from moisture,store under nitrogen,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (238.82 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.3422 mL	21.7108 mL	43.4216 mL	217.1081 mL
5 mM	0.8684 mL	4.3422 mL	8.6843 mL	43.4216 mL
10 mM	0.4342 mL	2.1711 mL	4.3422 mL	21.7108 mL
20 mM	0.2171 mL	1.0855 mL	2.1711 mL	10.8554 mL
50 mM	0.0868 mL	0.4342 mL	0.8684 mL	4.3422 mL
100 mM	0.0434 mL	0.2171 mL	0.4342 mL	2.1711 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc