Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-HAO1 Antibody (8R666)

😃Good
Catalog No. TMAY-02222
Alias hydroxyacid oxidase (glycolate oxidase) 1, HAOX1, GOX1, GOX

Anti-HAO1 Antibody (8R666) is a Rabbit antibody targeting HAO1. Anti-HAO1 Antibody (8R666) can be used in ELISA.

Anti-HAO1 Antibody (8R666)

Anti-HAO1 Antibody (8R666)

😃Good
Catalog No. TMAY-02222Alias hydroxyacid oxidase (glycolate oxidase) 1, HAOX1, GOX1, GOX
Anti-HAO1 Antibody (8R666) is a Rabbit antibody targeting HAO1. Anti-HAO1 Antibody (8R666) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
100 μL$269 7-10 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Anti-HAO1 Antibody (8R666) is a Rabbit antibody targeting HAO1. Anti-HAO1 Antibody (8R666) can be used in ELISA.
Aliashydroxyacid oxidase (glycolate oxidase) 1, HAOX1, GOX1, GOX
Ig Type
Monoclonal Rabbit IgG
Clone
8R666
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human HAO1 (rh HAO1; TMPY-01770; NP_060015.1; Leu 2-Ile 370).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundHydroxyacid oxidase 1, also known as Glycolate oxidase, HAO1, and GOX1, is a member of the FMN-dependent alpha-hydroxy acid dehydrogenase family. HAO1 / GOX1 has 2-hydroxyacid oxidase activity. It is most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. HAO1 / GOX1 is a liver-specific peroxisomal enzyme that oxidizes glycolate to glyoxylate with the concomitant production of H2O2. In Hao1 messenger RNA (mRNA), an iron-responsive element (IRE) homologous to the sequence recognized by iron regulatory proteins (IRP), key regulators of iron homeostasis, is present. Mammalian HAO1 / GOX1 is a peroxisomal protein and that the C-terminal sequence SKI acts as the targeting signal. Down-regulation of HAO1 / GOX1 expression during oxidative stress may provide a mechanism to prevent excessive H2O2 formation in liver peroxisomes and may represent the prototype of a poorly recognized but potentially relevant response to an oxidative injury involving down-regulation of ROS-producing enzymes.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human HAO1 / GOX1 protein (TMPY-01770)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

Sci Citations

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy Anti-HAO1 Antibody (8R666) | purchase Anti-HAO1 Antibody (8R666) | Anti-HAO1 Antibody (8R666) cost | order Anti-HAO1 Antibody (8R666)