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Anti-UBASH3A Antibody (9G35)

😃Good
Catalog No. TMAY-02632
Alias ubiquitin associated and SH3 domain containing A, TULA-1, TULA, STS-2, CLIP4

Anti-UBASH3A Antibody (9G35) is a Rabbit antibody targeting UBASH3A. Anti-UBASH3A Antibody (9G35) can be used in ELISA.

Anti-UBASH3A Antibody (9G35)

Anti-UBASH3A Antibody (9G35)

😃Good
Catalog No. TMAY-02632Alias ubiquitin associated and SH3 domain containing A, TULA-1, TULA, STS-2, CLIP4
Anti-UBASH3A Antibody (9G35) is a Rabbit antibody targeting UBASH3A. Anti-UBASH3A Antibody (9G35) can be used in ELISA.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-UBASH3A Antibody (9G35) is a Rabbit antibody targeting UBASH3A. Anti-UBASH3A Antibody (9G35) can be used in ELISA.
Aliasubiquitin associated and SH3 domain containing A, TULA-1, TULA, STS-2, CLIP4
Ig Type
Monoclonal Rabbit IgG
Clone
9G35
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human UBASH3A (rh UBASH3A; TMPY-03439; AAH69511.1; Ala354-Asn623).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundUBASH3A is a member of the T-cell ubiquitin ligand (TULA) family. This family consists of two members. Both of them can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of UBASH3A gene results in multiple transcript variants. It interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. UBASH3A promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. UBASH3A also exhibits negligigle protein tyrosine phosphatase activity at neutral pH. It may act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. It may also inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human UBASH3A Protein (TMPY-03439)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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