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Anti-UBASH3A Antibody (9G35)
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Catalog No. TMAY-02632
Alias ubiquitin associated and SH3 domain containing A, TULA-1, TULA, STS-2, CLIP4
Anti-UBASH3A Antibody (9G35) is a Rabbit antibody targeting UBASH3A. Anti-UBASH3A Antibody (9G35) can be used in ELISA.
Anti-UBASH3A Antibody (9G35)
Anti-UBASH3A Antibody (9G35)
😃Good
Catalog No. TMAY-02632Alias ubiquitin associated and SH3 domain containing A, TULA-1, TULA, STS-2, CLIP4
Anti-UBASH3A Antibody (9G35) is a Rabbit antibody targeting UBASH3A. Anti-UBASH3A Antibody (9G35) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Chemical Properties
| Description | Anti-UBASH3A Antibody (9G35) is a Rabbit antibody targeting UBASH3A. Anti-UBASH3A Antibody (9G35) can be used in ELISA. |
| Synonyms | ubiquitin associated and SH3 domain containing A, TULA-1, TULA, STS-2, CLIP4 |
| Ig Type | Rabbit IgG |
| Clone | 9G35 |
| Reactivity | Human |
| Specificity | Human UBASH3A |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human UBASH3A (rh UBASH3A; TMPY-03439; AAH69511.1; Ala354-Asn623). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | UBASH3A is a member of the T-cell ubiquitin ligand (TULA) family. This family consists of two members. Both of them can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of UBASH3A gene results in multiple transcript variants. It interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. UBASH3A promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. UBASH3A also exhibits negligigle protein tyrosine phosphatase activity at neutral pH. It may act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. It may also inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human UBASH3A Protein (TMPY-03439) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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