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Anti-UBASH3A Antibody (9G35) (Synonyms: ubiquitin associated and SH3 domain containing A, TULA-1, TULA, STS-2...)

Catalog No. TMAY-02632 Copy Product Info
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Anti-UBASH3A Antibody (9G35) is a Rabbit antibody targeting UBASH3A. Anti-UBASH3A Antibody (9G35) can be used in ELISA.

Anti-UBASH3A Antibody (9G35)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02632
Synonyms ubiquitin associated and SH3 domain containing A, TULA-1, TULA, STS-2, CLIP4

Anti-UBASH3A Antibody (9G35) is a Rabbit antibody targeting UBASH3A. Anti-UBASH3A Antibody (9G35) can be used in ELISA.

Anti-UBASH3A Antibody
(9G35)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-UBASH3A Antibody (9G35) is a Rabbit antibody targeting UBASH3A. Anti-UBASH3A Antibody (9G35) can be used in ELISA.
Synonymsubiquitin associated and SH3 domain containing A, TULA-1, TULA, STS-2, CLIP4
Ig Type
Rabbit IgG
Clone
9G35
Reactivity
Human
Specificity
Human UBASH3A
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human UBASH3A (rh UBASH3A; TMPY-03439; AAH69511.1; Ala354-Asn623).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundUBASH3A is a member of the T-cell ubiquitin ligand (TULA) family. This family consists of two members. Both of them can negatively regulate T-cell signaling. UBASH3A can facilitate growth factor withdrawal-induced apoptosis in T cells, which may occur via its interaction with AIF, an apoptosis-inducing factor. Alternative splicing of UBASH3A gene results in multiple transcript variants. It interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. UBASH3A promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface. UBASH3A also exhibits negligigle protein tyrosine phosphatase activity at neutral pH. It may act as a dominant-negative regulator of UBASH3B-dependent dephosphorylation. It may also inhibit dynamin-dependent endocytic pathways by functionally sequestering dynamin via its SH3 domain.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human UBASH3A Protein (TMPY-03439)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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