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Anti-CLEC-2 Antibody (2F242)
😃Good
Catalog No. TMAY-01394
Alias QDED721, PRO1384, C-type lectin domain family 1, member B, CLEC2B, CLEC2, 1810061I13Rik
Anti-CLEC-2 Antibody (2F242) is a Rabbit antibody targeting CLEC-2. Anti-CLEC-2 Antibody (2F242) can be used in ELISA.
Anti-CLEC-2 Antibody (2F242)
Anti-CLEC-2 Antibody (2F242)
😃Good
Catalog No. TMAY-01394Alias QDED721, PRO1384, C-type lectin domain family 1, member B, CLEC2B, CLEC2, 1810061I13Rik
Anti-CLEC-2 Antibody (2F242) is a Rabbit antibody targeting CLEC-2. Anti-CLEC-2 Antibody (2F242) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | QDED721, PRO1384, C-type lectin domain family 1, member B, CLEC2B, CLEC2, 1810061I13Rik |
| Ig Type | Rabbit IgG |
| Clone | 2F242 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human CLEC1B / CLEC2 (rh CLEC1B / CLEC2; TMPY-02357; Gln 58-Pro 229; NP_057593.3). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 acts as a receptor for the platelet-aggregating snake venom protein rhodocytin. Rhodocytin binding leads to tyrosine phosphorylation and this promotes the binding of spleen tyrosine kinase (Syk) and initiation of downstream tyrosine phosphorylation events and activation of PLC-gamma-2. CLEC2 contains 1 C-type lectin domain and is expressed preferentially in the liver. It acts as an attachment factor for human immunodeficiency virus type 1 (HIV-1) and facilitates its capture by platelets. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human CLEC1B / CLEC2 Protein (TMPY-02357) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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