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Anti-ICOS ligand Antibody (6Y133) (Alias: LICOS, inducible T-cell co-stimulator ligand, ICOSLG, ICOS-L, I...)
Catalog No. TMAY-01902 Copy Product Info
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Anti-ICOS ligand Antibody (6Y133) is a Mouse antibody targeting ICOS ligand. Anti-ICOS ligand Antibody (6Y133) can be used in ELISA(Cap).
Anti-ICOS ligand Antibody (6Y133)
Copy Product Info🥰Excellent
Catalog No. TMAY-01902
Alias LICOS, inducible T-cell co-stimulator ligand, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP-1, B7RP1, B7-h2, B7H2
Anti-ICOS ligand Antibody (6Y133) is a Mouse antibody targeting ICOS ligand. Anti-ICOS ligand Antibody (6Y133) can be used in ELISA(Cap).
Anti-ICOS ligand Antibody
(6Y133)
(6Y133)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μL | $69 | 7-10 days | 7-10 days | |
| 100 μL | $199 | 7-10 days | 7-10 days |
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-ICOS ligand Antibody (6Y133) is a Mouse antibody targeting ICOS ligand. Anti-ICOS ligand Antibody (6Y133) can be used in ELISA(Cap). |
| Synonyms | LICOS, inducible T-cell co-stimulator ligand, ICOSLG, ICOS-L, ICOSL, ICOS ligand, GL50, CD275, B7RP-1, B7RP1, B7-h2, B7H2 |
| Ig Type | Mouse IgG1 |
| Clone | 6Y133 |
| Reactivity | Human |
| Specificity | Human B7-H2/ICOSLG |
| Application | |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human ICOSL / ICOS ligand / B7-h2 (rh ICOSL / ICOS ligand / B7-h2; TMPY-01672; NP_056074.1; Met1-Ser258). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Inducible co-stimulator ligand (ICOSL), also known as B7-H2, is a member of the B7 family of co-stimulatory molecules related to B7-1 and B7-2. It is a transmembrane glycoprotein with extracellular IgV and IgC domains and binds to ICOS on activated T cells, thus delivers a positive costimulatory signal for optimal T cell function. The structural features of ICOSL are crucial for its costimulatory function. The present study shows that ICOSL displays a marked oligomerization potential, resembling more like B7-1 than B7-2. B7-H2-dependent signaling may play an active role in a proliferative response rather than in cytokine and chemokine production. The CD28/B7 and ICOS/B7-H2 pathways are both critical for costimulating T cell immune responses. Deficiency in either pathway results in defective T cell activation, cytokine production, and germinal center formation.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human ICOSL / ICOS ligand / B7-h2 Protein (TMPY-01672) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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