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Maltotetraose (Fujioligo 450) are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of early atherosclerosis development.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | $29 | In Stock | In Stock | |
| 10 mg | $48 | In Stock | In Stock | |
| 25 mg | $81 | In Stock | In Stock | |
| 50 mg | $139 | In Stock | In Stock |
| Description | Maltotetraose (Fujioligo 450) are potent inhibitors of TNF-α-induced intercellular adhesion molecule-1 (ICAM-1) expression, maltotetraose may be beneficial in the suppression of early atherosclerosis development. |
| In vivo | Maltotetraose reduced PDGF-induced sprout formation by mouse aorta explants and inhibited TNF-α-induced NF-κB activation and ICAM-1 expression in MOVAS-1 cells[1]. |
| Animal Research | Ex vivo migration of VSMCs was measured by aortic . Mouse thoracic aortas were excised from 8-week-old male Balb/c mice and adipose tissue was removed. The aortas were sectioned into 1-mm–long cross-sections, rinsed with serum-free DMEM, treated with 1 mg/mL collagenenase type II, placed in matrigel-coated wells, covered with 50 uL matrigel, and allowed to gel for more than 30 min at 37℃ in a 5% CO2 atmosphere. The aortic rings were treated with 20 ug/mL MALTOTETRAOSE for 30 min, followed by stimulation with 20 ng/mL PDGF-BB. Aortic ring sprouts were photographed on day 7[1]. |
| Synonyms | α-1,4-Tetraglucose, Fujioligo 450, Amylotetraose |
| Molecular Weight | 666.58 |
| Formula | C24H42O21 |
| Cas No. | 34612-38-9 |
| Smiles | OC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O[C@H]3[C@H](O)[C@@H](O)[C@@H](O[C@H]4[C@H](O)[C@@H](O)[C@@H](O)O[C@@H]4CO)O[C@@H]3CO)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@@H]1O |
| Relative Density. | 1.3922 g/cm3 (Estimated) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (82.51 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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