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SR 11302

Name: SR 11302
Brand: TargetMol
SKU: T23384
Price: 89 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T23384Cas No. 160162-42-5

SR 11302 is an inhibitor of activator protein-1 (AP-1).

SR 11302

🥰Excellent

Purity: 98.65%

Catalog No. T23384Cas No. 160162-42-5

SR 11302 is an inhibitor of activator protein-1 (AP-1).

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$89	-	In Stock
5 mg	$147	-	In Stock
10 mg	$228	-	In Stock
25 mg	$396	-	In Stock
50 mg	$653	-	In Stock
100 mg	$987	-	In Stock
1 mL x 10 mM (in DMSO)	$162	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:98.65%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	SR 11302 is an inhibitor of activator protein-1 (AP-1).
In vitro	SR 11302 can inhibit the growth of breast cancer cell line T-47D, the lung cancer line Calu-6, and HeLa cells. SR 11302 had very little effect on either the proliferation or the differentiation of HL-60, fresh APL, and NB4 cells[2].
In vivo	In an AP-1-luciferase transgenic mouse carcinogenesis model, SR11302 significantly inhibits both AP-1 activations in 7,12-dimethyl benz(a)anthracene-initiated mouse skin and 12-O-tetradecanoylphorbol-13-acetate-induced papilloma formation[3].

Chemical Properties

Molecular Weight	376.53
Formula	C₂₆H₃₂O₂
Cas No.	160162-42-5
Smiles	C\C(\C=C\C=C(\C=C\C1=C(C)CCCC1(C)C)/c1ccc(C)cc1)=C/C(O)=O
Relative Density.	1.048 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (132.79 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6558 mL	13.2792 mL	26.5583 mL	132.7915 mL
5 mM	0.5312 mL	2.6558 mL	5.3117 mL	26.5583 mL
10 mM	0.2656 mL	1.3279 mL	2.6558 mL	13.2792 mL
20 mM	0.1328 mL	0.6640 mL	1.3279 mL	6.6396 mL
50 mM	0.0531 mL	0.2656 mL	0.5312 mL	2.6558 mL
100 mM	0.0266 mL	0.1328 mL	0.2656 mL	1.3279 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc