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Cynaroside
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Catalog No. T3376Cas No. 5373-11-5
Alias Luteoloside, Luteolin 7-β-D-Glucopyranoside, Luteolin 7-O-β-D-glucoside, Luteolin 7-O-Glucoside, Luteolin 7-glucoside
Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.
Cynaroside
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Purity: 99.83%
Catalog No. T3376Alias Luteoloside, Luteolin 7-β-D-Glucopyranoside, Luteolin 7-O-β-D-glucoside, Luteolin 7-O-Glucoside, Luteolin 7-glucosideCas No. 5373-11-5
Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $30 | In Stock | In Stock | |
| 5 mg | $68 | In Stock | In Stock | |
| 10 mg | $105 | In Stock | In Stock | |
| 25 mg | $213 | In Stock | In Stock | |
| 50 mg | $376 | In Stock | In Stock | |
| 100 mg | $561 | In Stock | In Stock | |
| 200 mg | $796 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $77 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.83%
Color:Yellow
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Product Introduction
Cynaroside AI Summary
Cynaroside is a multifunctional agent that demonstrates a wide range of bioactivities. It effectively inhibits diphenolase activity of mushroom tyrosinase at 0.074 mM by 27.35%. The compound offers hepatoprotective properties against carbon tetrachloride-induced liver damage in rat hepatocytes by decreasing enzyme release. It exhibits antimicrobial action against Xanthomonas campestris with an inhibition zone of 3.0 mm at 0.5 mg/disk and displays similar activity against several other bacteria and fungi.
In terms of enzymatic inhibition, Cynaroside shows significant inhibition of cow milk xanthine oxidase and ACE in rabbit lung, along with moderate inhibitions of alpha-amylase and monoamine oxidase in mouse brain fractions. It possesses substantial antioxidant properties, demonstrated by ABTS, DPPH radical scavenging, and ferrous ion chelating activities. The compound also shows notable anti-inflammatory effects, inhibiting NO and PGE2 production in LPS-stimulated mouse RAW264.7 cells.
Interestingly, the compound presents antiviral activities against various viruses like EV71, Influenza A, B, and SARS-CoV-2, and inhibits neuraminidase activity of multiple influenza strains. It offers neuroprotective effects in human SH-SY5Y cells and has cytotoxic activities against several cancer cell lines including HL60, SW1573, and CEM.
Cynaroside shows binding affinities to significant proteins like Bcl-xL, IL-2, and TNF-alpha, highlighting its potential anti-cancer utility. It also exhibits antiamoebic activity and anti-inflammatory properties, further diversifying its pharmacological profile. Overall, Cynaroside presents various therapeutic potentials across antimicrobial, hepatoprotective, anti-inflammatory, antioxidant, enzyme inhibition, antiviral, and cytotoxic applications..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Cynaroside (Luteolin 7-O-Glucoside) is a flavone, a flavonoid-like chemical compound. It has an anti-oxidant effect, inhibiting lipid and protein oxidation. |
| Synonyms | Luteoloside, Luteolin 7-β-D-Glucopyranoside, Luteolin 7-O-β-D-glucoside, Luteolin 7-O-Glucoside, Luteolin 7-glucoside |
| Molecular Weight | 448.38 |
| Formula | C21H20O11 |
| Cas No. | 5373-11-5 |
| Smiles | OC[C@H]1O[C@@H](Oc2cc(O)c3c(c2)oc(cc3=O)-c2ccc(O)c(O)c2)[C@H](O)[C@@H](O)[C@@H]1O |
| Relative Density. | 1.713g/cm3 |
| Storage | keep away from direct sunlight,keep away from moisture,store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 83.33 mg/mL (185.85 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.46 mM), Sonication is recommended. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
RNASynthesisRNA SynthesisRNA polymerase inhibitorPKM2ParasiteLuteolin 7-O-beta-D-glucosideLuteolin 7-O-b-D-glucosideLuteolin 7-beta-D-GlucopyranosideLuteolin 7-b-D-GlucopyranosideInhibitorinhibitInfluenzaVirusInfluenza VirusFungalDNASynthesisDNA/RNA SynthesisDNA SynthesisCynarosidecardiovascularBacterialApoptosisantioxidantanti-inflammatoryantifungalanticancerantibacterialactivities
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Related Tags: buy Cynaroside | purchase Cynaroside | Cynaroside cost | order Cynaroside | Cynaroside chemical structure | Cynaroside formula | Cynaroside molecular weight
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