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NH2-C6-NH-Boc

Name: NH2-C6-NH-Boc
Brand: TargetMol
SKU: T18487
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T18487Cas No. 51857-17-1

NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].

NH2-C6-NH-Boc

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Purity: 99.97%

Catalog No. T18487Cas No. 51857-17-1

NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].

Pack Size	Price	Availability	Quantity
1 g	$29	In Stock

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Purity:99.97%

Resource Download

COA GC HNMR

Product Introduction

Bioactivity

Description

NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].

Chemical Properties

Molecular Weight	216.32
Formula	C₁₁H₂₄N₂O₂
Cas No.	51857-17-1
Smiles	C(NCCCCCCN)(OC(C)(C)C)=O
Relative Density.	0.965 g/cm3 at 20℃ (lit.)
Color	Transparent
Appearance	Liquid

Storage & Solubility Information

Storage

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

Ethanol: 100 mg/mL (462.28 mM), Sonication is recommended.

Solution Preparation Table

Ethanol

	1mg	5mg	10mg	50mg
1 mM	4.6228 mL	23.1139 mL	46.2278 mL	231.1391 mL
5 mM	0.9246 mL	4.6228 mL	9.2456 mL	46.2278 mL
10 mM	0.4623 mL	2.3114 mL	4.6228 mL	23.1139 mL
20 mM	0.2311 mL	1.1557 mL	2.3114 mL	11.5570 mL
50 mM	0.0925 mL	0.4623 mL	0.9246 mL	4.6228 mL
100 mM	0.0462 mL	0.2311 mL	0.4623 mL	2.3114 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc