ω-Conotoxin CVIF

Name: ω-Conotoxin CVIF
Brand: TargetMol
SKU: T80448
Rating: 4.5 (1 reviews)

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Catalog No. T80448

ω-Conotoxin CVIF is a selective inhibitor of Ca v 2.2 channels, with an IC50 value of 34.3 nM in isolated rat DRG neurons, and exhibits weakly reversible blockade of Cav2.2 channels [1].

ω-Conotoxin CVIF

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Catalog No. T80448

ω-Conotoxin CVIF is a selective inhibitor of Ca v 2.2 channels, with an IC50 value of 34.3 nM in isolated rat DRG neurons, and exhibits weakly reversible blockade of Cav2.2 channels [1].

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50 mg	Inquiry	Backorder

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Product Introduction

Bioactivity

Description

ω-Conotoxin CVIF is a selective inhibitor of Ca v 2.2 channels, with an IC50 value of 34.3 nM in isolated rat DRG neurons, and exhibits weakly reversible blockade of Cav2.2 channels [1].

Chemical Properties

Molecular Weight	2665.07
Formula	C₁₀₁H₁₇₀N₄₀O₃₃S₆
Sequence	Cys-Lys-Gly-Lys-Gly-Ala-Ser-Cys-Arg-Arg-Thr-Ser-Tyr-Asp-Cys-Cys-Thr-Gly-Ser-Cys-Arg-Leu-Gly-Arg-Cys-NH2 (Disulfide bridge:Cys1-Cys16, Cys8-Cys20 and Cys15-Cys27)
Sequence Short	CKGKGASCRRTSYDCCTGSCRLGRC-NH2 (Disulfide bridge:Cys1-Cys16, Cys8-Cys20 and Cys15-Cys27)

Storage & Solubility Information

Storage

keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc