Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JKE-1716 is an inhibitor of glutathione peroxidase 4 (GPX4) and a derivative of the GPX4 inhibitor ML-210 .1JKE-1716 reduces viability of LOX-IMVI cancer cells in a concentration-dependent manner and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 .
Description | JKE-1716 is an inhibitor of glutathione peroxidase 4 (GPX4) and a derivative of the GPX4 inhibitor ML-210 .1JKE-1716 reduces viability of LOX-IMVI cancer cells in a concentration-dependent manner and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1 . |
Molecular Weight | 451.3 |
Formula | C20H20Cl2N4O4 |
CAS No. | 2421118-05-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
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JKE-1716 2421118-05-8 JKE 1716 JKE1716 inhibitor inhibit