Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

Jarin-1

😃Good
Catalog No. T15608Cas No. 1212704-51-2

Jarin-1, a jasmonic acid-amido synthetase (JAR1) inhibitor (IC50: 3.8 μM), specifically suppresses bioactive JA biosynthesis in Arabidopsis and other plants.

Jarin-1

Jarin-1

😃Good
Purity: 99.82%
Catalog No. T15608Cas No. 1212704-51-2
Jarin-1, a jasmonic acid-amido synthetase (JAR1) inhibitor (IC50: 3.8 μM), specifically suppresses bioactive JA biosynthesis in Arabidopsis and other plants.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$72In StockIn Stock
5 mg$197In StockIn Stock
10 mg$328In StockIn Stock
25 mg$558In StockIn Stock
50 mg$788In StockIn Stock
100 mg$1,120-In Stock
1 mL x 10 mM (in DMSO)$213In StockIn Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:99.82%
Contact us for more batch information

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity
Description
Jarin-1, a jasmonic acid-amido synthetase (JAR1) inhibitor (IC50: 3.8 μM), specifically suppresses bioactive JA biosynthesis in Arabidopsis and other plants.
In vitro
MeJA + Jarin-1 treatment caused an upregulation of FaANR and associated transcription factors such as FabHLH33 and FaMYB9/11 along with FaJMT and FaJAR1.2. JA-responsive elements in the promoter regions of FaMYB1/9/10/11 genes are found. The proanthocyanidin (PA) content was higher in Jarin-1- and MeJA + Jarin-1-treated than in MeJA-treated fruits. PA biosynthesis-related genes can be upregulated by the application of Jarin-1 to MeJA-treated fruit, thus increasing PA accumulation in strawberry. A higher redness of strawberry fruit skin and anthocyanin content in MeJA-treated fruits with respect to Jarin-1-treated ones concomitant with an upregulation of FaANS and FaUFGT genes is found [1].
Chemical Properties
Molecular Weight471.55
FormulaC28H29N3O4
Cas No.1212704-51-2
Smiles[H][C@@]12CN(C[C@@]([H])(C1)c1ccc(NC(=O)c3ccc(cc3)-c3ccccc3)c(=O)n1C2)C(=O)CCOC
Relative Density.1.31 g/cm3 (Predicted)
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 30.6 mg/mL (64.89 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.24 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1207 mL10.6033 mL21.2067 mL106.0333 mL
5 mM0.4241 mL2.1207 mL4.2413 mL21.2067 mL
10 mM0.2121 mL1.0603 mL2.1207 mL10.6033 mL
20 mM0.1060 mL0.5302 mL1.0603 mL5.3017 mL
50 mM0.0424 mL0.2121 mL0.4241 mL2.1207 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Jasmonic acid-amido synthetase (JAR1)Jarin-1Jarin1Jarin 1
Related Tags: buy Jarin-1 | purchase Jarin-1 | Jarin-1 cost | order Jarin-1 | Jarin-1 chemical structure | Jarin-1 in vitro | Jarin-1 formula | Jarin-1 molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.