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Cucurbitacin Q1

Name: Cucurbitacin Q1
Brand: TargetMol
SKU: TN2341
Price: 81 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN2341Cas No. 99530-82-2

Cucurbitacin Q1 is identified as the fruit of Cucumis prophetarum and has been shown to be the pure trans component of cucurbitacin Q.

Cucurbitacin Q1

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🥰Excellent

Purity: 99.89%

Catalog No. TN2341Cas No. 99530-82-2

Cucurbitacin Q1 is identified as the fruit of Cucumis prophetarum and has been shown to be the pure trans component of cucurbitacin Q.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$81	In Stock	In Stock
5 mg	$197	In Stock	In Stock
10 mg	$313	In Stock	In Stock
25 mg	$562	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$255	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.89%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Cucurbitacin Q1 AI Summary

Cucurbitacin Q1 exhibits cytotoxicity against human cancer cell lines MCF7, H460, and SF268 with GI50 values of 110.0 nM, 65.0 nM, and 87.0 nM, respectively. It also shows cytotoxicity against human HT-29 cells, with an IC50 value of 540.0 nM in a sulforhodamine B assay conducted over 3 days..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

Cucurbitacin Q1 is identified as the fruit of Cucumis prophetarum and has been shown to be the pure trans component of cucurbitacin Q.

Chemical Properties

Molecular Weight	560.72
Formula	C₃₂H₄₈O₈
Cas No.	99530-82-2
Smiles	[H][C@@]1([C@H](O)C[C@@]2(C)[C@]3([H])CC=C4[C@@]([H])(C[C@H](O)[C@@H](O)C4(C)C)[C@]3(C)C(=O)C[C@]12C)[C@@](C)(O)C(=O)\C=C\C(C)(C)OC(C)=O
Relative Density.	1.23 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (115.92 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7834 mL	8.9171 mL	17.8342 mL	89.1711 mL
5 mM	0.3567 mL	1.7834 mL	3.5668 mL	17.8342 mL
10 mM	0.1783 mL	0.8917 mL	1.7834 mL	8.9171 mL
20 mM	0.0892 mL	0.4459 mL	0.8917 mL	4.4586 mL
50 mM	0.0357 mL	0.1783 mL	0.3567 mL	1.7834 mL
100 mM	0.0178 mL	0.0892 mL	0.1783 mL	0.8917 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc