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Tetraethylene glycol

Name: Tetraethylene glycol
Brand: TargetMol
SKU: T16662
Rating: 4.5 (1 reviews)

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Catalog No. T16662Cas No. 112-60-7

Alias PROTAC Linker 18

Tetraethylene glycol is a PEG-based PROTAC linker that can be oxidised as a substrate of polyethylene glycol dehydrogenase (Km = 10 mM).

Tetraethylene glycol

🥰Excellent

Catalog No. T16662Alias PROTAC Linker 18Cas No. 112-60-7

Tetraethylene glycol is a PEG-based PROTAC linker that can be oxidised as a substrate of polyethylene glycol dehydrogenase (Km = 10 mM).

Pack Size	Price	Availability	Quantity
100 mg	Inquiry	In Stock
500 mg	Inquiry	In Stock

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Resource Download

COA HNMR

Product Introduction

Bioactivity

Description	Tetraethylene glycol is a PEG-based PROTAC linker that can be oxidised as a substrate of polyethylene glycol dehydrogenase (Km = 10 mM).
Alias	PROTAC Linker 18

Chemical Properties

Molecular Weight	194.23
Formula	C₈H₁₈O₅
Cas No.	112-60-7
Smiles	OCCOCCOCCOCCO
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (411.88 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.1485 mL	25.7427 mL	51.4854 mL	257.4268 mL
5 mM	1.0297 mL	5.1485 mL	10.2971 mL	51.4854 mL
10 mM	0.5149 mL	2.5743 mL	5.1485 mL	25.7427 mL
20 mM	0.2574 mL	1.2871 mL	2.5743 mL	12.8713 mL
50 mM	0.1030 mL	0.5149 mL	1.0297 mL	5.1485 mL
100 mM	0.0515 mL	0.2574 mL	0.5149 mL	2.5743 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc