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11-Oxoisomogroside V (compound 3), a cucurbitacin derived from Luo Han Guo extract, enhances the transcriptional activity of PGC-1α. Luciferase assay data demonstrates that at concentrations of 10 μM and 20 μM, 11-Oxoisomogroside V increases luciferase activity to 133.79% and 143.81%, respectively [1].

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | 11-Oxoisomogroside V (compound 3), a cucurbitacin derived from Luo Han Guo extract, enhances the transcriptional activity of PGC-1α. Luciferase assay data demonstrates that at concentrations of 10 μM and 20 μM, 11-Oxoisomogroside V increases luciferase activity to 133.79% and 143.81%, respectively [1]. |
| Molecular Weight | 1285.42 |
| Formula | C60H100O29 |
| Cas No. | 2149606-15-3 |
| Smiles | C[C@]12[C@]([C@@]3(C)[C@](C)(CC1=O)[C@@]([C@@H](CC[C@@H](O[C@H]4[C@H](O[C@@H]5O[C@H](CO)[C@@H](O)[C@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@@H](CO[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O)O4)C(C)(C)O)C)(CC3)[H])(CC=C7[C@]2(CC[C@H](O[C@@H]8O[C@H](CO)[C@@H](O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)[C@H](O)[C@H]8O)C7(C)C)[H])[H] |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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