Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TIE-2/VEGFR-2 kinase-IN-1 is used for the synthesis of TIE-2 and/or VEGFR-2 inhibitors that can be used for the study of diseases associated with inappropriate angiogenesis [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,350.00 | |
50 mg | 6-8 weeks | $ 1,760.00 | |
100 mg | 6-8 weeks | $ 2,680.00 |
Description | TIE-2/VEGFR-2 kinase-IN-1 is used for the synthesis of TIE-2 and/or VEGFR-2 inhibitors that can be used for the study of diseases associated with inappropriate angiogenesis [1]. |
In vitro | Angiopoietin-1, a ligand for the endothelium-specific receptor tyrosine kinase TIE-2, represents a novel angiogenic factor [1]. Inhibiting TIE-2 could disrupt the remodeling and maturation of new vasculature that angiogenesis initiates. Similarly, targeting the kinase domain binding site of VEGFR-2 to block tyrosine residue phosphorylation could hinder the onset of angiogenesis. |
Molecular Weight | 241.25 |
Formula | C13H11N3O2 |
CAS No. | 453590-24-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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TIE-2/VEGFR-2 kinase-IN-1 453590-24-4 TIE 2/VEGFR 2 kinase IN 1 TIE2/VEGFR2 kinaseIN1 inhibitor inhibit