Contact UsQuotation
Shopping Cart
Remove All
  • TargetMol
    Your shopping cart is currently empty
Proceed to checkoutContinue shopping
TOPBioactivityChemical infoStorage&SolubilityCalculator

WNK1-IN-1

🥰Excellent
Catalog No. T73295Cas No. 324022-39-1
Alias WNK1-IN1

WNK1-IN-1 is a selective WNK1 (With No lysine (K) 1) inhibitor (IC50 = 1.6 μM) that inhibits the phosphorylation of the endogenous substrate OSR1, and can be used to study hypertension and cancer.

WNK1-IN-1

WNK1-IN-1

🥰Excellent
Purity: 98.09%
Catalog No. T73295Alias WNK1-IN1Cas No. 324022-39-1
WNK1-IN-1 is a selective WNK1 (With No lysine (K) 1) inhibitor (IC50 = 1.6 μM) that inhibits the phosphorylation of the endogenous substrate OSR1, and can be used to study hypertension and cancer.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$68-In Stock
5 mg$163-In Stock
10 mg$263-In Stock
25 mg$538-In Stock
50 mg$868-In Stock
100 mg$1,450-In Stock
1 mL x 10 mM (in DMSO)$179-In Stock
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
TargetMol
View More

Batch Information

Select Batch
Purity:98.09%
Contact us for more batch information

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity
Description
WNK1-IN-1 is a selective WNK1 (With No lysine (K) 1) inhibitor (IC50 = 1.6 μM) that inhibits the phosphorylation of the endogenous substrate OSR1, and can be used to study hypertension and cancer.
In vitro
WNK1-IN-1 (0.2-12.5 μM, 24 hours) treats endogenous OSR1 phosphorylated MDAMB231 breast cancer cells with an IC50 value of 4.3 μM. [1]
SynonymsWNK1-IN1
Chemical Properties
Molecular Weight446.14
FormulaC13H15BrCl2N2O4S
Cas No.324022-39-1
Smiles[O-][N+](C1=CC(S(=O)(C(Br)(Cl)Cl)=O)=CC=C1NC2CCCCC2)=O
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (179.32 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+90% Corn Oil: 3.3 mg/mL (7.4 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.2414 mL11.2072 mL22.4145 mL112.0724 mL
5 mM0.4483 mL2.2414 mL4.4829 mL22.4145 mL
10 mM0.2241 mL1.1207 mL2.2414 mL11.2072 mL
20 mM0.1121 mL0.5604 mL1.1207 mL5.6036 mL
50 mM0.0448 mL0.2241 mL0.4483 mL2.2414 mL
100 mM0.0224 mL0.1121 mL0.2241 mL1.1207 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy WNK1-IN-1 | purchase WNK1-IN-1 | WNK1-IN-1 cost | order WNK1-IN-1 | WNK1-IN-1 chemical structure | WNK1-IN-1 in vitro | WNK1-IN-1 formula | WNK1-IN-1 molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.