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Anti-Chymase 1 Antibody (7I538)
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Catalog No. TMAC-02479
Anti-Chymase 1 Antibody (7I538) is a Rabbit antibody targeting Chymase 1. Anti-Chymase 1 Antibody (7I538) can be used in WB,IHC.
Anti-Chymase 1 Antibody (7I538)
Anti-Chymase 1 Antibody (7I538)
😃Good
Catalog No. TMAC-02479
Anti-Chymase 1 Antibody (7I538) is a Rabbit antibody targeting Chymase 1. Anti-Chymase 1 Antibody (7I538) can be used in WB,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $498 | 7-10 days |
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Chymase 1 Antibody (7I538) is a Rabbit antibody targeting Chymase 1. Anti-Chymase 1 Antibody (7I538) can be used in WB,IHC. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Mast Cell Chymase, also known as CMA1 or MCT1, is a major secreted serine protease that is involved in vasoactive peptide generation, extracellular matrix degradation and regulation of gland secretion. The human chymase gene, which maps to human chromosome 14q11.2, encodes a preproenzyme with a 19 amino acid signal peptide, an acidic 2 amino acid propeptide and a 226 amino acid catalytic domain. Mast Cell Chymase is a chymotryptic serine proteinase which is a member of the peptidase family S1. Expressed in mast cells, Mast Cell Chymase is associated with the degradation of the extracellular matrix, the regulation of submucosal gland secretion, and the generation of vasoactive peptides. Mast cell proteases are a family of rodent protein homologs to human tryptases that are specifically expressed in mast cells and may serve as highly specific markers in the analysis of mast cell heterogeneity, differentiation and function. Mast Cell Protease 1, also designated Mcp-1 or Mcpt1, is a rodent specific beta-chymase. The mouse and rat Mast Cell Protease 1 proteins share 76% sequence identity at the amino acid level. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Antigen Species | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 27 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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