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Firocoxib

Name: Firocoxib
Brand: TargetMol
SKU: T7596
Price: 33 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T7596Cas No. 189954-96-9

Alias ML 1785713

Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cyclooxygenase-2 (COX-2) with an IC50 of 0.13 μM, used for its anti-inflammatory properties in dogs and horses.

Firocoxib

🥰Excellent

Purity: 99.84%

Catalog No. T7596Alias ML 1785713Cas No. 189954-96-9

Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cyclooxygenase-2 (COX-2) with an IC50 of 0.13 μM, used for its anti-inflammatory properties in dogs and horses.

Pack Size	Price	Availability
1 mg	$33	In Stock
5 mg	$68	In Stock
10 mg	$111	In Stock
25 mg	$215	In Stock
50 mg	$318	In Stock
100 mg	$477	In Stock
1 mL x 10 mM (in DMSO)	$77	In Stock

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Batch Information

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Purity:99.84%

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COA LCMS HNMR

Product Introduction

Bioactivity

Description	Firocoxib (ML 1785713) is a selective non-steroidal inhibitor of cyclooxygenase-2 (COX-2) with an IC50 of 0.13 μM, used for its anti-inflammatory properties in dogs and horses.
Targets&IC50	COX-1:7.5 μM, COX-2:0.13 μM
Synonyms	ML 1785713

Chemical Properties

Molecular Weight	336.4
Formula	C₁₇H₂₀O₅S
Cas No.	189954-96-9
Smiles	O(CC1CC1)C2=C(C(C)(C)OC2=O)C3=CC=C(S(C)(=O)=O)C=C3
Relative Density.	1.31 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 47 mg/mL (139.71 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9727 mL	14.8633 mL	29.7265 mL	148.6326 mL
5 mM	0.5945 mL	2.9727 mL	5.9453 mL	29.7265 mL
10 mM	0.2973 mL	1.4863 mL	2.9727 mL	14.8633 mL
20 mM	0.1486 mL	0.7432 mL	1.4863 mL	7.4316 mL
50 mM	0.0595 mL	0.2973 mL	0.5945 mL	2.9727 mL
100 mM	0.0297 mL	0.1486 mL	0.2973 mL	1.4863 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc