Powder: -20°C for 3 years | In solvent: -80°C for 1 year
NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent charge and low membrane permeability. It exhibits minimal cytotoxicity against Ovcar-8 and MCF-10A cell lines (IC50 <100 μM) and maintains hERG channel maturation without eliciting a heat shock response or degrading Hsp90α-dependent client proteins [1].
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Description | NDNA4 (compound 17) is a selective Hsp90α inhibitor (IC50: 0.34 μM), characterized by its permanent charge and low membrane permeability. It exhibits minimal cytotoxicity against Ovcar-8 and MCF-10A cell lines (IC50 >100 μM) and maintains hERG channel maturation without eliciting a heat shock response or degrading Hsp90α-dependent client proteins [1]. |
Molecular Weight | 604.68 |
Formula | C31H35F3N2O5S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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NDNA4 Cytoskeletal Signaling Metabolism HSP inhibitor inhibit