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Engeletin

1. Engeletin (Dihydrokaempferol 3-rhamnoside) may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant human aldose reductase (IC5 value=1.16 microM).

Catalog No. T6S0840Cas No. 572-31-6

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Purity:99.99%

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COA HNMR HPLC

Engeletin

Catalog No. T6S0840Cas No. 572-31-6

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Pack Size	Price	Availability
5 mg	$41	In Stock
10 mg	$67	In Stock
25 mg	$148	In Stock
50 mg	$238	In Stock
100 mg	$423	In Stock
1 mL x 10 mM (in DMSO)	$45	In Stock

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Product Introduction

Bioactivity

Description	1. Engeletin (Dihydrokaempferol 3-rhamnoside) may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant human aldose reductase (IC5 value=1.16 microM).
Alias	Dihydrokaempferol 3-rhamnoside

Chemical Properties

Molecular Weight	434.39
Formula	C₂₁H₂₂O₁₀
Cas No.	572-31-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

Pyridine, Methanol, etc.: Soluble

DMSO: 78 mg/mL (179.6 mM)

Ethanol: Soluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3021 mL	11.5104 mL	23.0208 mL	115.1039 mL
5 mM	0.4604 mL	2.3021 mL	4.6042 mL	23.0208 mL
10 mM	0.2302 mL	1.1510 mL	2.3021 mL	11.5104 mL
20 mM	0.1151 mL	0.5755 mL	1.1510 mL	5.7552 mL
50 mM	0.0460 mL	0.2302 mL	0.4604 mL	2.3021 mL
100 mM	0.0230 mL	0.1151 mL	0.2302 mL	1.1510 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc