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(+)-(3R,8S)-Falcarindiol

Name: (+)-(3R,8S)-Falcarindiol
Brand: TargetMol
SKU: T5S1285
Price: 39 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T5S1285Cas No. 225110-25-8

Alias Falcarindiol

1. (+)-(3R,8S)-Falcarindiol is a potential new anticancer agent that exerts its activity through inducing ER stress and apoptosis. 2. Falcarindiol induces immunosuppressive effects in vitro and in vivo and might be a novel therapy for autoimmune or allergic diseases. 3. Falcarindiol has protective effect against CCl(4) toxicity , in part, be explained by anti-lipid peroxidation activity associated with the induction of the GSTs including GSTA4.

(+)-(3R,8S)-Falcarindiol

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Purity: 97.06%

Catalog No. T5S1285Alias FalcarindiolCas No. 225110-25-8

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$39	-	In Stock
5 mg	$123	In Stock	In Stock
10 mg	$197	-	In Stock
25 mg	$332	-	In Stock
50 mg	$496	-	In Stock
100 mg	$693	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:97.06%

Appearance:Liquid

Color:Yellow

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	1. (+)-(3R,8S)-Falcarindiol is a potential new anticancer agent that exerts its activity through inducing ER stress and apoptosis. 2. Falcarindiol induces immunosuppressive effects in vitro and in vivo and might be a novel therapy for autoimmune or allergic diseases. 3. Falcarindiol has protective effect against CCl(4) toxicity , in part, be explained by anti-lipid peroxidation activity associated with the induction of the GSTs including GSTA4.
Targets&IC50	Mycobacterium tuberculosisH37Ra:6 μM (IC50)
Synonyms	Falcarindiol

Chemical Properties

Molecular Weight	260.37
Formula	C₁₇H₂₄O₂
Cas No.	225110-25-8
Smiles	CCCCCCC\C=C/[C@H](O)C#CC#C[C@H](O)C=C
Relative Density.	1.000 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight | Pure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 60 mg/mL (230.44 mM), Sonication is recommended.

Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (7.68 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.8407 mL	19.2034 mL	38.4069 mL	192.0344 mL
5 mM	0.7681 mL	3.8407 mL	7.6814 mL	38.4069 mL
10 mM	0.3841 mL	1.9203 mL	3.8407 mL	19.2034 mL
20 mM	0.1920 mL	0.9602 mL	1.9203 mL	9.6017 mL
50 mM	0.0768 mL	0.3841 mL	0.7681 mL	3.8407 mL
100 mM	0.0384 mL	0.1920 mL	0.3841 mL	1.9203 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc