Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Ar-V7-IN-1

😃Good
Catalog No. T61820Cas No. 2230880-25-6

Ar-V7-IN-1 (compound 47) is a potent inhibitor of Ar-V7, a genetic mRNA splice variant of the androgen receptor (AR) associated with resistance to AR-targeted therapy in patients with desmoplasia-resistant prostate cancer (mCRPC).

Ar-V7-IN-1

Ar-V7-IN-1

😃Good
Catalog No. T61820Cas No. 2230880-25-6
Ar-V7-IN-1 (compound 47) is a potent inhibitor of Ar-V7, a genetic mRNA splice variant of the androgen receptor (AR) associated with resistance to AR-targeted therapy in patients with desmoplasia-resistant prostate cancer (mCRPC).
Pack SizePriceAvailabilityQuantity
25 mg$767 6-8 weeks
50 mg$997 6-8 weeks
100 mg$1,740 6-8 weeks
Add to Cart
Add to Quotation
Bulk & Custom
Questions
View More
Select Batch
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Ar-V7-IN-1 (compound 47) is a potent inhibitor of Ar-V7, a genetic mRNA splice variant of the androgen receptor (AR) associated with resistance to AR-targeted therapy in patients with desmoplasia-resistant prostate cancer (mCRPC).
Chemical Properties
Molecular Weight394.09
FormulaC10H10Br2N4OS
Cas No.2230880-25-6
SmilesBrC=1N=CN(C1Br)C=2N=C(SC2)N3CCOCC3
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 80 mg/mL (203 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.5375 mL12.6875 mL25.3749 mL126.8746 mL
5 mM0.5075 mL2.5375 mL5.0750 mL25.3749 mL
10 mM0.2537 mL1.2687 mL2.5375 mL12.6875 mL
20 mM0.1269 mL0.6344 mL1.2687 mL6.3437 mL
50 mM0.0507 mL0.2537 mL0.5075 mL2.5375 mL
100 mM0.0254 mL0.1269 mL0.2537 mL1.2687 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Ar-V7-IN-1 | purchase Ar-V7-IN-1 | Ar-V7-IN-1 cost | order Ar-V7-IN-1 | Ar-V7-IN-1 chemical structure | Ar-V7-IN-1 formula | Ar-V7-IN-1 molecular weight