Zorubicin

Name: Zorubicin
Brand: TargetMol
SKU: T69130
Rating: 4.5 (1 reviews)

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Catalog No. T69130Cas No. 54083-22-6

Alias Rubidazone, Rubidazon ; Rubidazone, Rubidazon

Zorubicin (Rubidazon), a Daunorubicin derivative, inhibits DNA polymerases and interacts with topoisomerase II. It is utilized in the research of acute leukemias and sarcomas [1] [2] [3] [4] [5].

Zorubicin

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Catalog No. T69130Alias Rubidazone, Rubidazon ; Rubidazone, RubidazonCas No. 54083-22-6

Zorubicin (Rubidazon), a Daunorubicin derivative, inhibits DNA polymerases and interacts with topoisomerase II. It is utilized in the research of acute leukemias and sarcomas [1] [2] [3] [4] [5].

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$4,520	10-14 weeks	10-14 weeks
50 mg	$5,980	10-14 weeks	10-14 weeks
100 mg	$8,500	10-14 weeks	10-14 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	Zorubicin (Rubidazon), a Daunorubicin derivative, inhibits DNA polymerases and interacts with topoisomerase II. It is utilized in the research of acute leukemias and sarcomas [1] [2] [3] [4] [5].
In vitro	H2-Gamendazole (H2-GMZ; 0-100 μM) was effective in rapidly blocking forskolin-induced, Cl-mediated short-circuit currents in human ADPKD cells, and it significantly inhibited both cAMP- and epidermal growth factor-induced proliferation of ADPKD cells.[1] H2-GMZ (50 μM)-treated ADPKD cells showed decreased phosphorylated ERK and decreased hyperphosphorylated retinoblastoma levels through western blot analysis.[1] H2-GMZ (50 μM; 24、48、72 h) treatment also decreased ErbB2, Akt, and cyclin-dependent kinase 4 and it decreased levels of the cystic fibrosis transmembrane conductance regulator Cl channel protein.[1]
In vivo	H2-Gamendazole (20 mg/kg; intraperitoneal injections) was effective in slowing postnatal cyst formation and kidney enlargement in the ---Pkd1flox/flox: Pkhd1-Cre mouse model.[1]
Synonyms	Rubidazone, Rubidazon ; Rubidazone, Rubidazon

Chemical Properties

Molecular Weight	645.66
Formula	C₃₄H₃₅N₃O₁₀
Cas No.	54083-22-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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