Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CFTR corrector 8 is a highly effective modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). This compound is specifically designed for utilization in research related to cystic fibrosis, a genetic disorder primarily affecting the lungs and digestive system [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 272.00 | |
5 mg | In stock | $ 677.00 | |
10 mg | In stock | $ 963.00 | |
25 mg | In stock | $ 1,430.00 | |
50 mg | In stock | $ 1,930.00 | |
100 mg | In stock | $ 2,590.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 987.00 |
Description | CFTR corrector 8 is a highly effective modulator of the cystic fibrosis transmembrane conductance regulator (CFTR). This compound is specifically designed for utilization in research related to cystic fibrosis, a genetic disorder primarily affecting the lungs and digestive system [1]. |
In vitro |
CFTR corrector 8 demonstrates EC50 values of 1 μM in the CSE-HRP assay and 3 μM in the HBE-TECC assay.[1] CFTR corrector 8 displays a hepatocyte clearance rate of 1250 L/hr/kg in humans and 775 L/hr/kg in rats.[1] |
Molecular Weight | 539.52 |
Formula | C29H27F2NO7 |
CAS No. | 1918142-35-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (18.53 mM)
You can also refer to dose conversion for different animals. More
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CFTR corrector 8 1918142-35-4 Membrane transporter/Ion channel CFTR inhibitor inhibit