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Anti-FLT1 Antibody (6K171)
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Catalog No. TMAY-00326
Alias VEGFR-1, VEGFR1, fms-related tyrosine kinase 1, FLT-1, FLT
Anti-FLT1 Antibody (6K171) is a Mouse antibody targeting FLT1. Anti-FLT1 Antibody (6K171) can be used in ELISA,ICC/IF.
Anti-FLT1 Antibody (6K171)
Anti-FLT1 Antibody (6K171)
😃Good
Catalog No. TMAY-00326Alias VEGFR-1, VEGFR1, fms-related tyrosine kinase 1, FLT-1, FLT
Anti-FLT1 Antibody (6K171) is a Mouse antibody targeting FLT1. Anti-FLT1 Antibody (6K171) can be used in ELISA,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $68 | 7-10 days | |
| 100 μL | $198 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-FLT1 Antibody (6K171) is a Mouse antibody targeting FLT1. Anti-FLT1 Antibody (6K171) can be used in ELISA,ICC/IF. |
| Alias | VEGFR-1, VEGFR1, fms-related tyrosine kinase 1, FLT-1, FLT |
| Ig Type | Monoclonal Mouse IgG2a |
| Clone | 6K171 |
| Reactivity | Human |
| Verified Activity | Immunofluorescence staining of Human VEGFR1 in Hela cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Mouse anti-Human VEGFR1 monoclonal antibody (dilution ratio 1:60) at 37°C 1 hour. Then cells were stained with the Alexa Fluor®488-conjugated Goat Anti-mouse IgG secondary antibody. Positive staining was localized to plasma membrane. |
| Application | ELISA,ICC/IF |
| Recommended Dose | ELISA: 1:1000-1:2000; ICC-IF: 1:20-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human VEGFR1 / FLT-1 (rh VEGFR1 / FLT-1; TMPY-02108; P17948-1; Met 1-Asn 756). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS with 10% Trehalose, 0.02% Tween 80, pH7.0 |
| Research Background | Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a single-pass type I membrane protein and secreted protein which belongs to theprotein kinase superfamily, Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 / FLT1 contains sevenIg-like C2-type (immunoglobulin-like) domains and oneprotein kinase domain. VEGFR-1 / FLT1 is expressed mostly in normal lung, but also in placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cells, and also expressed in peripheral blood monocytes. VEGFR-1 / FLT1 is not expressed in tumor cell lines. VEGFR-1 / FLT1 is an essential receptor tyrosine kinase that regulates mammalian vascular development and embryogenesis. EGF-induced angiogenesis requires inverse regulation of VEGFR-1 and VEGFR-2 in tumor-associated endothelial cells. VEGFR-1 / FLT1 is a receptor for VEGF, VEGFB and PGF. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human VEGFR1 / FLT-1 protein (TMPY-02108) |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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