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DCZ3301

Name: DCZ3301
Brand: TargetMol
SKU: T9658
Price: 70 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9658Cas No. 2136278-38-9

Alias NPS ALX Compound 4a hydrochloride(1:1)(299433-10-6 Free base)

DCZ3301 is a novel aryl-guanidino inhibitor.

DCZ3301

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Purity: 99.89%

Catalog No. T9658Alias NPS ALX Compound 4a hydrochloride(1:1)(299433-10-6 Free base)Cas No. 2136278-38-9

DCZ3301 is a novel aryl-guanidino inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$70	In Stock	In Stock
5 mg	$161	In Stock	In Stock
10 mg	$237	In Stock	In Stock
25 mg	$355	In Stock	In Stock
50 mg	$500	In Stock	In Stock
100 mg	$672	In Stock	In Stock
200 mg	$890	-	In Stock
1 mL x 10 mM (in DMSO)	$178	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Batch Information

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Purity:99.89%

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	DCZ3301 is a novel aryl-guanidino inhibitor.
In vitro	Jurkat and HUT78 cells was markedly inhibited by DCZ3301 treatment in a time- and dose- dependent manner, IC50 values for Jurkat and HUT78 cells were 3.02 μM and 9.42 μM, respectively, after DCZ3301 treatment for 48 h.
Synonyms	NPS ALX Compound 4a hydrochloride(1:1)(299433-10-6 Free base)

Chemical Properties

Molecular Weight	464.83
Formula	C₂₀H₁₆ClF₃N₆O₂
Cas No.	2136278-38-9
Smiles	O(C=1C=C(C(NC)=O)N=CC1)C=2C=CC(NC(NC3=CC(C(F)(F)F)=C(Cl)C=C3)=N)=NC2
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (107.57 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 2.5 mg/mL (5.38 mM), Sonication is recommeded.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1513 mL	10.7566 mL	21.5132 mL	107.5662 mL
5 mM	0.4303 mL	2.1513 mL	4.3026 mL	21.5132 mL
10 mM	0.2151 mL	1.0757 mL	2.1513 mL	10.7566 mL
20 mM	0.1076 mL	0.5378 mL	1.0757 mL	5.3783 mL
50 mM	0.0430 mL	0.2151 mL	0.4303 mL	2.1513 mL
100 mM	0.0215 mL	0.1076 mL	0.2151 mL	1.0757 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc