Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SIRT-IN-3, a potent inhibitor of SIRT1 with an IC50 value of 17 μM, exhibits approximate 4-fold and 14-fold greater selectivity for SIRT1 over SIRT2 and SIRT3, with respective IC50 values of 74 μM for SIRT2 and 235 μM for SIRT3 [1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mL * 10 mM (in DMSO) | 5 days | $ 54.00 |
Description | SIRT-IN-3, a potent inhibitor of SIRT1 with an IC50 value of 17 μM, exhibits approximate 4-fold and 14-fold greater selectivity for SIRT1 over SIRT2 and SIRT3, with respective IC50 values of 74 μM for SIRT2 and 235 μM for SIRT3 [1]. |
In vitro | SIRT-IN-3 (Compound 7) (30-300 μM; 8 hours) leads p53 acetylation in HCT116 cells [1]. |
Molecular Weight | 212.25 |
Formula | C13H12N2O |
CAS No. | 1211-19-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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SIRT-IN-3 1211-19-4 inhibitor inhibit